Fred Upton

With this hearing, we are going to continue our commitment to modernizing laws and regulations to keep pace with the breakneck speed of the innovation era.

This is a very serious hearing for sure.

The administration should never have gone live last fall in the first place without the Web site being structurally complete.

For months and even years, the alarms were sounding over the president's health care law that it was not ready for prime time and that it would not work for the American people.

I look forward to working with you on both of those accounts and move it to regular order through the authorization process. Certainly that is an issue that I want to see our committee deal with in the next Congress for sure.

The entire purpose of our 21st Century Cures initiative is to accelerate the discovery, development, and delivery of safe and effective treatments to America's patients.

Safety is always the top priority, and I believe we can safely do better; we must work together to remove any needless administrative or operational burdens that do not benefit patients.

This system is simply unsustainable.

At our first 21st Century Cures roundtable, we learned that there are treatments for only 500 of the more than 7,000 known diseases affecting our Nation's patients.

Safety is always the top priority. And I know, I know that we can do better.

This means that new treatments and cures cost more and they are getting to patients more slowly. That system is simply unsustainable.

Because of advances in technology and innovation, we are now entering a new era of abundance. America is emerging, yes, as an energy superpower. We can enjoy the domestic benefits of being an energy superpower while also projecting our…

We should not pay potential fraudsters a dime, let alone the billions we actually do.

How can the government continue losing tens of billions of taxpayer dollars every year?

Our goal is to save taxpayer dollars and strengthen the program.

The system failed and people died, and it could have been prevented.

A culture that allowed safety problems to fester for years will be hard to change, but if GM is going to recover and regain the public's trust, it has to learn from this report and break the patterns that led to this unimaginable…

I find it very disturbing and downright devastating to you, to GM, to folks in Michigan who live and breathe pride in the auto industry, but most of all to the families of the victims.

You have my word that we will do our best to make sure that this kind of tragedy will never, never happen again.

We need to show the American public that the changes that have been announced will really address the longstanding problems at GM.

The jury is still out on whether we can have success in changing the culture.

This latest recall raises even more questions about just how pervasive safety problems are at GM.

We have got to heed the advice of the President's Council of Advisors and take a fresh look at current and potential economic incentives to promote innovation.

It is clear that our work is far from over. We lack effective treatments for almost 95 percent of the known diseases affecting patients today and over 95 percent of drugs in development do not make it to market.

We did launch the 21st Century Cures Initiative with the goal of accelerating the discovery, development, and delivery of innovative new treatments and cures to patients, ensuring that the United States remains the biomedical innovation…