01/28/1982
https://www.presidency.ucsb.edu...
"That is a gift to mankind we can be very proud of."
"I am pleased to sign into law today the Orphan Drug Act."
"By definition, an orphan drug is one that treats a disease that affects 200,000 or fewer individuals."
"This legislation exemplifies the proper role of government in helping meet legitimate needs in those cases where the free market alone can't do the job."