We've been off the mark for 20 years.

The Promising Pathway Act is a commonsense step to give the FDA the flexibility it needs to serve Americans with these most trying diseases.

The budget problems of our country could be solved... in a couple weeks of legislative time.

We've been off the mark for 20 years.

That is why we need the formality of PPA.

All we want as an alternative to certain death is a pathway that allows us access to these therapies at the point where safety and promising evidence and effectiveness have been established.

I think if not, you're at least not going to be in a position where you have credibility to offer other things to do.

Since I've been here no one understands that in this institution.

These diseases are relentless. They are widespread and devastating.

Patients deserve a promising pathway at the FDA.

I have been working on this for most of the five-years I have been here in the Senate.

We borrow now 30 cents on every dollar we spend.

Would the Promising Pathways Act address that in a way that would be meaningful, so we at least keep businesses in business to try to work on these ailments?

We've given up our energy independence. We've done so many things that tilt the whole analysis.

We borrow now 30 cents on every dollar we spend. Just 5 years ago that was 20 cents.

I have no question that those policies would be much more costly than any reasonable benefits we'd get in any other area, including climate policy.

I think I can think of nothing more dangerous and disastrous for our near term and medium term energy outlook, and national security outlook than were we to effectively make peak supply real by banning investment in new oil and gas…

Since I've been here no one understands that in this institution. That is why we borrow aggressively for the latest and greatest political idea that you think might parlay into a solution.

That's a calamity that will far swamp anything that we've been talking about here.

I'm a conservative that believes we need to be in the discussion of climate.

The fact that we haven't done that in 20-some years makes this very much an academic discussion.

I'm simply asking for one thing. That is transparency throughout the system, like we have in all other markets.

I was finally sick and tired of hearing how lucky I was that my premiums are only going up 5 to 10 percent a year.

Obamacare gave us, I think, some things that address the fact that everybody should have access.

Prevention is worth--an ounce of that is worth a pound of cure.