Andy Burnham: “Obviously it's difficult, given the financial circumstances in which we find ourselves.”

If the UK wants to build global companies, we need to be globally competitive. To do that, we cannot have Britain's start-ups simply sell up.

Politics has become too suffocating. We need greater ambition. The country is not where it should be and nothing simple gets us out of that. We need to show a journey and a longer-term plan.

We can do it, and we can be the nation in the next 10 years that… does find the cure for cancer, that does make the breakthrough on dementia, or indeed on nuclear fusion.

I want Britain to be the country that makes the breakthrough and delivers the cure for dementia the world has been waiting for.